Severe complications in colorectal cancer screening colonoscopies in the Valencian Community

Autor: Ibáñez J, Vanaclocha-Espí M, Pérez-Sanz E, Valverde MJ, Sáez-Lloret I, Molina-Barceló A, Salas D, Grupo de Trabajo del Programa de Prevención de Cáncer Colorrectal de la Comunita
Rok vydání: 2018
Předmět:
Zdroj: GASTROENTEROLOGIA Y HEPATOLOGIA
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
ISSN: 0210-5705
Popis: Objective: To identify and characterise the severe complications of diagnostic confirmation colonoscopies carried out as part of the Colorectal Cancer Screening Program of the Valencian Community (CCSP-VC). Method: A retrospective observational study from 2005 to 2012. To identify complications, the CCSP-VC information system was used, as well as Spanish Minimum Basic Data Set hospital discharge summaries and medical records. Cumulative incidence rates were estimated for all complications, immediate complications (occurring the same day as the colonoscopy) and delayed complications (occurring 1-30 days after the colonoscopy) for the 1,000 colonoscopies performed. A bivariate analysis using the Chi-square test was performed for the onset of complications, according to gender, age and type of test (guaiac/immunological), as welt as for the complication onset time (immediate/delayed) based on the type of colonoscopy (diagnostic/therapeutic) and type of complication (haemorrhage/perforation). Results: Of the total 8,831 screening colonoscopies performed, 23 severe complications were observed, 13 of which were perforations (56.5%) and 10 haemorrhages (43.5%). No serious vagal syndrome, peritonitis or deaths were recorded. The cumulative incidence rate was 2.60 parts per thousand; 2.85 parts per thousand for the guaiac test and 2.56 parts per thousand for the immunological test. The incidence rate was higher in men (2.93 parts per thousand) than in women (2.16 parts per thousand), as well as in older groups (3.02 parts per thousand versus 1.98 parts per thousand). Of the total complications, 61% (n = 14) were immediate. Conclusions: The severe complication rates of screening colonoscopies are a quality indicator for population-based colorectal cancer screening programs that require extensive research in order to maintain the appropriate risk/benefit ratio of such programs. (C) 2018 Elsevier Espana, S.L.U. All rights reserved.
Databáze: OpenAIRE