Transdiagnostic neurocognitive deficits in patients with type 2 diabetes mellitus, major depressive disorder, bipolar disorder, and schizophrenia: A 1-year follow-up study

Autor: Correa-Ghisays P, Sánchez-Ortí JV, Balanzá-Martínez V, Selva-Vera G, Vila-Francés J, Magdalena-Benedito R, Victor VM, Escribano-López I, Hernández-Mijares A, Vivas-Lalinde J, San-Martín C, Crespo-Facorro B, Tabarés-Seisdedos R
Rok vydání: 2022
Předmět:
Zdroj: JOURNAL OF AFFECTIVE DISORDERS
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-FISABIO. Repositorio Institucional de Producción Científica
ISSN: 0165-0327
Popis: BACKGROUND: Neurocognition impairments are critical factors in patients with major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia (SZ), and also in those with somatic diseases such as type 2 diabetes mellitus (T2DM). Intriguingly, these severe mental illnesses are associated with an increased co-occurrence of diabetes (direct comorbidity). This study sought to investigate the neurocognition and social functioning across T2DM, MDD, BD, and SZ using a transdiagnostic and longitudinal approach. METHODS: A total of 165 participants, including 30 with SZ, 42 with BD, 35 with MDD, 30 with T2DM, and 28 healthy controls (HC), were assessed twice at a 1-year interval using a comprehensive, integrated test battery on neuropsychological and social functioning. RESULTS: Common neurocognitive impairments in somatic and psychiatric disorders were identified, including deficits in short-term memory and cognitive reserve (p
Databáze: OpenAIRE
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