Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021
| Autor: | Ruan, Alexandra, Tobin, Nicole H, Mulligan, Kathleen, Rollie, Adrienne, Li, Fan, Sleasman, John, Aldrovandi, Grace M |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Adolescent Clinical Sciences Antiretroviral Therapy HIV Infections sVCAM 2.2 Factors relating to physical environment bone Young Adult Sex Factors Bone Density Clinical Research macrophage activation Virology Humans 2.2 Factors relating to the physical environment Highly Active Absorptiometry Aetiology IL-6 Puerto Rico HIV sCD14 Photon Spine United States Cross-Sectional Studies Infectious Diseases Public Health and Health Services Osteoporosis HIV/AIDS Female Metabolic Bone Diseases Infection |
| Zdroj: | Journal of acquired immune deficiency syndromes (1999), vol 72, iss 4 |
| Popis: | Accumulating evidence suggests that rates of low bone mass are greater in HIV-infected males than females. Of 11 biomarkers assessed by sex and HIV-status, HIV-infected males had increased levels of soluble CD14 which inversely correlated with bone mineral content and bone mineral density measures, suggesting macrophage activation as a possible mechanism of differential bone loss. |
| Databáze: | OpenAIRE |
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