CLINICAL SIGNIFICANCE OF 5αα-REDUCTASE AND ANDROGEN RECEPTOR GENE POLYMORPHISMS IN PROSTATE CANCER
| Autor: | O. B. Loran, I. V. Lukyanov, D. Yu. Tuzov, A. N. Tyulpakov |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Onkourologiâ, Vol 5, Iss 1, Pp 48-52 (2014) Onkourologiâ, Vol 5, Iss 1, Pp 48-52 (2009) |
| ISSN: | 1996-1812 1726-9776 |
| Popis: | The development of prostate cancer is inseparably linked with the effect of androgens on the fundamental prostatic intracellular processes,such as proliferation, apoptosis, which is realized through a number of second messengers. Major of them are the AR gene encoding androgenreceptors and the SRD5A2 gene encoding 5α-reductase enzyme. This paper deals with the study of the role of these genes in prostate cancer. |
| Databáze: | OpenAIRE |
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