MWASTools:An R/bioconductor package for metabolome-wide association studies
| Autor: | Rodriguez Martinez, A, Posma, JM, Ayala, R, Neves, AL, Anwar, M, Petretto, E, Emanueli, C, Gauguier, D, Nicholson, JK, Dumas, M |
|---|---|
| Přispěvatelé: | Commission of the European Communities, Medical Research Council, Imperial College Healthcare NHS Trust- BRC Funding |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Rodriguez-Martinez, A, Posma, J M, Ayala, R, Neves, A L, Anwar, M, Petretto, E, Emanueli, C, Gauguier, D, Nicholson, J K & Dumas, M E 2018, ' MWASTools : An R/bioconductor package for metabolome-wide association studies ', Bioinformatics, vol. 34, no. 5, pp. 890-892 . https://doi.org/10.1093/bioinformatics/btx477 |
| DOI: | 10.1093/bioinformatics/btx477 |
| Popis: | Summary: MWASTools is an R package designed to provide an integrated pipeline to analyze metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of MWAS results. Availability: The MWASTools R package is implemented in R (version > =3.4) and is available from Bioconductor: https://bioconductor.org/packages/MWASTools/ |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|