Artificial membranes for membrane protein purification, functionality and structure studies

Autor: Parmar, MJ, De Marcos Lousa, C, Muench, SP, Goldman, A, Postis, VLG
Jazyk: angličtina
Rok vydání: 2016
ISSN: 0300-5127
Popis: Membrane proteins represent one of the most important targets for pharmaceutical companies. Unfortunately, technical limitations have long been a major hindrance in our understanding of the function and structure of such proteins. Recent years have seen the refinement of classical approaches and the emergence of new technologies that have resulted in a significant step forward in the field of membrane protein research. This review summarises some of the current techniques used for studying membrane proteins, with overall advantages and drawbacks for each method.
Databáze: OpenAIRE