Reagentless and sub-minute laser-scribing treatment to produce enhanced disposable electrochemical sensors via additive manufacture

Autor: Siervo, Abner de, 1972
Přispěvatelé: UNIVERSIDADE ESTADUAL DE CAMPINAS
Rok vydání: 2021
Předmět:
Zdroj: Repositório da Produção Científica e Intelectual da Unicamp
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
Repositório Institucional da Unicamp
ISSN: 7172-2017
Popis: Agradecimentos: This research was supported by Sao Paulo Research Foundation (FAPESP) (Grant numbers: 2007/08244-5, 2007/54829-5, 2014/50867-3, 2017/18574-4, 2018/08782-1, 2018/14462-0 2018/16896-7, and 2020/00325-0), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) (Pró-Forenses Edital 25/2014) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) (Grant Number: 305605/2017-8, 307172-2017-0, 311847/2018-8, 465389/2014-7 – INCTBio and 302839/2020-8). We would like to thank the undergraduate student Rodrigo Ramos for the help with the video recording. The authors are also grateful to Central Analítica (IQ/USP) for the SEM infrastructure. We would also like to thank Dr. Gabriel N. Meloni and Dr. Carla S. Santos for the graphical abstract illustration Abstract: 3D printing is the most popular form of additive manufacturing, and conductive 3D-printed platforms have been recognized as an emerging class of devices with high potential for electrochemistry. Nevertheless, as-printed electrodes provide poor conductivity due to the presence of high amounts of insulating thermoplastic material, requiring surface post-treatments to enhance their electrochemical performance. Such treatments often employ non-eco-friendly, costly, and time-consuming protocols. In this regard, we propose, for the first time, a sub-minute (around 50 s) and reagentless surface treatment of carbon-black/PLA-based 3D-printed electrodes using a Photo-Thermal approach by a CO2 laser. After the proposed treatment (optimized conditions: the power of 6.2%, the scan rate of 20 mm s-1, and height of 10 mm), a marked improvement in the electrochemical electrode response (current increase and peak-to-peak separation) was achieved towards the detection of catechol, ascorbic and uric acids, paracetamol, hexaammineruthenium(III) chloride, and Ferri/ferrocyanide redox couple. The enhanced simultaneous determination of Cd2+, Pb2+, and Cu2+ was also demonstrated. As a proof-of-concept, the quantification of the adulterant paracetamol in a real seized cocaine sample was performed using a fully 3D-printed electrochemical system, and a good recovery value of 97.8% was acquired. To explain all the improved results, the electrode was carefully characterized by imaging, spectroscopic and electrochemical techniques. Additionally, the between-measurement % relative standard deviation (%RSD) was 6.8% (n = 12), while the between-device %RSD was 7.5% (n = 6) at the 1 µmol L-1 paracetamol, indicating adequate manufacturing reproducibility. Thus, the strategies developed here open up new possibilities for applications of carbon-based 3D-printed electrodes in analytical electrochemistry FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPES CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQ Fechado
Databáze: OpenAIRE
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