Diffusion tensor imaging, intracranial vascular resistance and cognition in middle-aged asymptomatic subjects
| Autor: | López-Olóriz J, López-Cancio E, Arenillas JF, Hernández M, Dorado L, Dacosta-Aguayo R, Barrios M, Soriano-Raya JJ, Miralbell J, Bargalló N, Cáceres C, Torán P, Alzamora M, Dávalos A, Mataro M |
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| Rok vydání: | 2014 |
| Zdroj: | CEREBROVASCULAR DISEASES r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu |
| ISSN: | 1015-9770 |
| Popis: | The contribution of traditional vascular risk factors to cognitive impairment and dementia is well known. However, in order to obtain possible targets for prevention of vascular cognitive impairment (VCI), it may be important to identify other early and noninvasive markers in asymptomatic middle-aged adults. The calculation of middle cerebral artery-pulsatility index (MCA-PI) is an ultrasonologic, noninvasive, validated and easily reproducible technique to assess increased distal resistance to blood flow. This study aims to assess the relationship between MCA-PI, microstructural white matter (WM) integrity and cognition in a middle-aged asymptomatic population. |
| Databáze: | OpenAIRE |
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