Mediterranean diet and risk of heart failure: results from the PREDIMED randomized controlled trial
| Autor: | Papadaki, Angeliki, Martínez-González, Miguel Ángel, 1957, Alonso Gómez, Ángel M., Rekondo, Javier, Salas Salvadó, Jordi, Corella Piquer, Dolores, Ros Rahola, Emilio, Fitó Colomer, Montserrat, Estruch Riba, Ramon, Lapetra, José, García Rodriguez, Antonio, Fiol Sala, Miguel, Serra Majem, Lluís, Pintó Sala, Xavier, Ruiz-Canela, Miguel, Bulló, Mònica, Serra-Mir, Mercè, Sorlí, José V., Arós, Fernando |
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| Přispěvatelé: | Universitat de Barcelona |
| Předmět: |
Male
AF atrial fibrillation Heart diseases BMI body mass index Statistics as Topic HDL high-density lipoprotein Heart failure T2D type 2 diabetes CVD cardiovascular disease Diet Mediterranean CHD coronary heart disease Risk Assessment HF heart failure Malalties del cor Mediterranean cooking PAD peripheral arterial disease Mediterranean diet LDL low-density lipoprotein Cuina mediterrània Humans Nuts FFQ food frequency questionnaire PREDIMED Prevención con Dieta Mediterránea Olive Oil Dieta -- Mediterrània Regió de la Aged Heart Failure EVOO extra virgin olive oil Incidence WtHR waist-to-height ratio PREDIMED study Middle Aged Cardiovascular disease Cardiac arrest Aturada cardíaca MedDiet Mediterranean diet Infart de miocardi Outcome and Process Assessment Health Care Cardiovascular Diseases Dietary Supplements MI myocardial infarction Female |
| Zdroj: | Recercat. Dipósit de la Recerca de Catalunya instname Papadaki, A, Martínez-González, M Á, Alonso-Gómez, A, Rekondo, J, Salas-Salvadó, J, Corella, D, Ros, E, Fitó, M, Estruch, R, Lapetra, J, García-Rodriguez, A, Fiol, M, Serra-Majem, L, Pintó, X, Ruiz-Canela, M, Bulló, M, Serra-Mir, M, Sorlí, J V & Arós, F 2017, ' Mediterranean diet and risk of heart failure : Results from the PREDIMED randomized controlled trial ', European Journal of Heart Failure, vol. 19, no. 9, pp. 1179-1185 . https://doi.org/10.1002/ejhf.750 Dipòsit Digital de la UB Universidad de Barcelona |
| DOI: | 10.1002/ejhf.750 |
| Popis: | Aims: The aim of this study was to evaluate the effect of the Mediterranean diet (MedDiet) on the incidence of heart failure (HF), a pre-specified secondary outcome in the PREDIMED (PREvención con DIeta MEDiterránea) primary nutrition-intervention prevention trial. Methods and results: Participants at high risk of cardiovascular disease were randomly assigned to one of three diets: MedDiet supplemented with extra-virgin olive oil (EVOO), MedDiet supplemented with nuts, or a low-fat control diet. Incident HF was ascertained by a Committee for Adjudication of events blinded to group allocation. Among 7403 participants without prevalent HF followed for a median of 4.8 years, we observed 29 new HF cases in the MedDiet with EVOO group, 33 in the MedDiet with nuts group, and 32 in the control group. No significant association with HF incidence was found for the MedDiet with EVOO and MedDiet with nuts, compared with the control group [hazard ratio (HR) 0.68; 95% confidence interval (CI) 0.41-1.13, and HR 0.92; 95% CI 0.56-1.49, respectively]. Conclusion: In this sample of adults at high cardiovascular risk, the MedDiet did not result in lower HF incidence. However, this pre-specified secondary analysis may have been underpowered to provide valid conclusions. Further randomized controlled trials with HF as a primary outcome are needed to better assess the effect of the MedDiet on HF risk. Trial registration: ISRCTN35739639. |
| Databáze: | OpenAIRE |
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