Selective carboxylate directed ortho functionalization in copper catalyzed reactions of polyiodo aromatics: A straightforward preparation of 5,7-diiodo-1H-isochromen-1-ones

Autor: Anselmi, Elsa, Bahlaouan, Zineb, Ngi, Samuel Inack, Parrain, Jean Luc, Magnier, Emmanuel, Abarbri, Mohamed
Přispěvatelé: Infectiologie et Santé Publique (UMR ISP), Institut National de la Recherche Agronomique (INRA)-Université de Tours, Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU), Institut National de la Recherche Agronomique (INRA)-Université de Tours (UT)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2017, pp.6131-6136. ⟨10.1002/ejoc.201700859⟩
European Journal of Organic Chemistry, 2017, 41, pp.6131-6136. ⟨10.1002/ejoc.201700859⟩
ISSN: 1434-193X
1099-0690
DOI: 10.1002/ejoc.201700859⟩
Popis: International audience; A facile, and totally regioselective one-pot approach to synthesize 5,7-diiodo-3-substituted-isocoumarins is described. This reaction was realized by using copper iodide as the catalyst under mild reaction conditions. The methodology was used to design a wide variety of compounds and was tolerant to a large number of functional groups. Interestingly, among the three possible carbon-iodine bonds, only one was reactive, which left the two others intact for further functionalization.
Databáze: OpenAIRE
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