| Autor: |
Inzaule, Seth C, Jordan, Michael R, Bello, George, Wadonda-Kabondo, Nellie, Mounerou, Salou, Mbulli, Innocent A, Akanmu, Sulaimon A, Vubil, Adolfo, Hunt, Gillian, Kaleebu, Pontiano, Mthethwa-Hleza, Simangele, Dzangare, Janet, Njukeng, Patrick, Penazzato, Martina, Rinke de Wit, Tobias F, Eshleman, Susan H, Bertagnolio, Silvia, Infant HIV Drug Resistance Survey Team |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| ISSN: |
0269-9370 |
| Popis: |
Exposure of infants to antiretroviral drugs for prevention of mother-to-child transmission can induce resistance to nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). Data from nine national surveys of pretreatment drug resistance in children newly diagnosed with HIV show high levels of resistance to NRTIs included in first-line antiretroviral treatment (ART) regimens (dual abacavir-lamivudine/emtricitabine resistance). Additional research is needed to determine the impact of NRTI resistance on treatment response and optimize infant ART. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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