| Autor: |
Bonell, Ana, Azarrafiy, Ryan, Huong, Vu Thi Lan, Viet, Thanh Le, Phu, Vu Dinh, Dat, Vu Quoc, Wertheim, Heiman, van Doorn, H Rogier, Lewycka, Sonia, Nadjm, Behzad |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| ISSN: |
1058-4838 |
| Popis: |
Background: Ventilator-associated pneumonia (VAP) is the commonest hospital-acquired infection (HAI) in intensive care. In Asia, VAP is increasingly caused by resistant gram-negative organisms. Despite the global antimicrobial resistance crisis, the epidemiology of VAP is poorly documented in Asia. Methods: We systematically reviewed literature published on Ovid Medline, Embase Classic, and Embase from 1 January 1990 to 17 August 2017 to estimate incidence, prevalence, and etiology of VAP. We performed a meta-analysis to give pooled rates and rates by country income level. Results: Pooled incidence density of VAP was high in lower- and upper-middle-income countries and lower in high-income countries (18.5, 15.2, and 9.0 per 1000 ventilator-days, respectively). Acinetobacter baumannii (n = 3687 [26%]) and Pseudomonas aeruginosa (n = 3176 [22%]) were leading causes of VAP; Staphylococcus aureus caused 14% (n = 1999). Carbapenem resistance was common (57.1%). Conclusions: VAP remains a common cause of HAI, especially in low- and middle-income countries, and antibiotic resistance is high. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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