Autor: |
Abongo, Bernard, Gimnig, John E, Torr, Steve, Longman, Bradley, Omoke, Diana, Muchoki, Margaret, terKuile, Feiko, Ochomo, Eric, Munga, Stephen, Samuels, Aaron M, Njiagi, Kiambo, Maas, James, Perry, Robert T, Fornadel, Christen, Donnelly, Martin, Oxborough, Richard M |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
|
ISSN: |
2045-2322 |
Popis: |
Indoor residual spraying (IRS) of insecticides is a major vector control strategy for malaria prevention. We evaluated the impact of a single round of IRS with the organophosphate, pirimiphos-methyl (Actellic 300CS), on entomological and parasitological parameters of malaria in Migori County, western Kenya in 2017, in an area where primary vectors are resistant to pyrethroids but susceptible to the IRS compound. Entomological monitoring was conducted by indoor CDC light trap, pyrethrum spray catches (PSC) and human landing collection (HLC) before and after IRS. The residual effect of the insecticide was assessed monthly by exposing susceptible An. gambiae s.s. Kisumu strain to sprayed surfaces in cone assays and measuring mortality at 24 hours. Malaria case burden data were extracted from laboratory records of four health facilities within the sprayed area and two adjacent unsprayed areas. IRS was associated with reductions in An. funestus numbers in the intervention areas compared to non-intervention areas by 88% with light traps (risk ratio [RR] 0.12, 95% CI 0.07–0.21, p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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