How common is truly benign MS in a UK population?

Autor: Tallantyre, Emma Clare, Major, Paula C., Atherton, Michael J., Davies, W. Adam, Joseph, Fady, Tomassini, Valentina, Pickersgill, Trevor P., Harding, Katharine E., Willis, Mark Douglas, Winter, Mia, Robertson, Neil P.
Jazyk: angličtina
Rok vydání: 2018
ISSN: 0022-3050
Popis: Objectives The prevalence and definition of benign multiple sclerosis (BMS) remain controversial. Most definitions are based on the Expanded Disability Status Scale (EDSS), not encompassing the wider impact of disease. The explanation for favourable outcomes remains unclear. We aim to provide a detailed characterisation of patients with low EDSS scores at long disease durations.\ud \ud Methods We screened a population-based registry containing 3062 people with MS to identify individuals with unlimited walking ability at disease durations >15 years. A representative cohort underwent detailed clinical assessment and classified as having BMS according to EDSS score 15 years, 200 (19.1%) had most recent EDSS score
Databáze: OpenAIRE