| Autor: |
Sommerville, C., Richardson, J.M., Williams, R.A.M., Mottram, J.C., Roberts, C.W., Alexander, J., Henriquez, F.L. |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| ISSN: |
0021-9258 |
| Popis: |
Background: Toxoplasma gondii possesses proteins that can modulate host immune responses. TgMIF is a homologue of mammalian macrophage migration inhibitory factor.\ud \ud Results: TgMIF possesses tautomerase but not oxidoreductase activity. It can stimulate ERK MAPK and IL-8 production.\ud \ud Conclusion: TgMIF is capable of modulating host molecules.\ud \ud Significance: The study identifies immunomodulatory activity of TgMIF consistent with a role for sustaining parasite survival. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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