Use of fluorescent optical fibre probe for recording parameters of brain metabolism in rat model

Autor: Alekseyev, Alexander, Seryogina, Evgeniya, Stelmashchuk, Olga, Zherebtsov, Evgeny A., Piavchenko, Gennadii, Vorobyev, Evgeny, Kuznetsova, Elena, Rafailov, Edik U., Kuznetsova, Alyona, Dunaev, Andrey, Rafailov, Ilya, Tuchin, Valery V.
Přispěvatelé: Popp, Jürgen, Pavone, Francesco S.
Jazyk: angličtina
Rok vydání: 2018
Zdroj: Proceedings of SPIE
Popis: This studiy was carried out on groups of clinically healthy male Wistar rats. Animals received distilled drinking water ad libitum for 1 month, water containing succinic acid, water containing zinc sulphate and succinate zinc. Using the method of fluorescence spectroscopy, the parameters of brain metabolism in vivo in a model of laboratory rats was investigated. Based on data obtained by fluorescence spectroscopy, we have registered a change in the degree of cellular respiration in different structures of the cerebral cortex with the toxic effect of zinc compounds and succinic acid on the oxygen exchange process.
Databáze: OpenAIRE