Characterization and cytotoxicity studies of thiol-modified polystyrene microbeads doped with [(Mo6X8)(NO3)6]2- (X=Cl, Br, I)

Autor: Vorotnikova, Natalya A., Efremova, Olga A., Tsygankova, Alphiya R., Brylev, Konstantin A., Edeleva, Mariya V., Kurskaya, Olga G., Sutherland, Andrew J., Shestopalov, Alexandr M., Mironov, Yuri V., Shestopalov, Michael A.
Jazyk: angličtina
Rok vydání: 2016
ISSN: 1099-1581
Popis: Halide octahedral molybdenum clusters [(Mo6X8)L6]n- possess luminescence properties that are highly promising for biological applications. These properties are rather dependent on the nature of both the inner ligands X (i.e. Cl, Br, or I) and the apical organic or inorganic ligands L. Herein, the luminescence properties and the toxicity of thiol-modified polystyrene microbeads (PS-SH) doped with [(Mo6X8)(NO3)6]2- (X=Cl, Br, I) were studied and evaluated using human epidermoid larynx carcinoma (Hep2) cell cultures. According to our data, the photoluminescence quantum yield of (Mo6I8)@PS-SH is significantly higher (0.04) than that of (Mo6Cl8)@PS-SH (6Br8)@PS-SH (6X8)@PS-SH showed that all three types of doped microbeads had no significant effect on the viability and proliferation of the cells.
Databáze: OpenAIRE