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Use of anhydrous caffeine is an established and widely used ergogenic method. In sprinting events, optimum performance is highly dependent on the simultaneous peak functioning of a host of physiological systems. Therefore, caffeine supplementation protocols need to be perfectly timed in order to achieve culmination in sprint performance parameters within a narrow time window. Typically, caffeine capsules are ingested approximately 1 h before exercise however absorption rates may be highly variable. An alternative mode of ingestion is through caffeinated gum where caffeine is rapidly absorbed through the buccal mucosa. Our aim was to investigate the acute effects of two distinct modes of caffeine ingestion on sprint performance. Following ethics approval, eight trained male sprinters aged 20.2 (±0.8) took part in a screening and familiarisation session before they completed four trials (3x40 m sprints with 4 min recovery between runs) a week apart. A double-blind randomized crossover design was adopted where, during the trials, participants received: 1) Caffeine gum (CAFG, 6 mg.kg-1 of body weight), 2) CAFG placebo (CAFGP), 3) Caffeine capsules (CAFC, mg.kg-1 of body weight), 4) CAFC placebo (CAFCP). General and sport-specific warm-up commenced 15 minutes before sprint one. Capsules were given 45 minutes and chewing gums 15 minutes before sprint one. The gums were chewed for 5 minutes. Blood lactate and glucose concentration, heart rate, arousal and feeling levels were recorded at baseline and different time points during testing. Mean time to complete the three sprints were 5.00(±0.23), 5.03(±0.17), 5.10(±0.15), and 5.10(±0.14) seconds for the CAFG, CAFC, CAFGP and CAFCP conditions respectively. Participants ran significantly faster (p |