Understanding Dorsoventral Topography Backwards and Forwards
| Autor: | Pittman, Andrew J, Chien, Chi-Bin |
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| Jazyk: | angličtina |
| Předmět: | |
| Zdroj: | Neuron. (3):409-411 |
| ISSN: | 0896-6273 |
| DOI: | 10.1016/S0896-6273(02)00797-3 |
| Popis: | Retinal axons project to their central targets along two orthogonal topographic axes, anterior-posterior (A-P) and dorsal-ventral (D-V). While ephrin-A/EphA signaling determines A-P topography, little has been known about the molecular mechanisms guiding axons along the D-V axis. Two papers by Mann et al. and Hindges et al. in this issue of Neuron provide evidence for both forward and reverse ephrin-B/EphB signaling in regulating D-V topography. |
| Databáze: | OpenAIRE |
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