| Autor: |
Graves, Patricia M, Makita, Leo, Susapu, Melinda, Brady, Molly A, Melrose, Wayne, Capuano, Corinne, Zhang, Zaixing, Dapeng, Luo, Ozaki, Masayo, Reeve, David, Ichimori, Kazuyo, Kazadi, Walter M, Bockarie, Moses, Kelly-Hope, Louise |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
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| ISSN: |
1756-3305 |
| Popis: |
BACKGROUND\ud \ud Lymphatic filariasis (LF) caused by Wuchereria bancrofti is present at high prevalence in some parts of Papua New Guinea. However, there has been no rigorous data-based representative assessment of nationwide prevalence of LF. The LF programme has been daunted by the scope of the problem, and progress on mass drug administration (MDA) has been slow and lacking in resources. \ud \ud METHODS\ud \ud A systematic literature review identified LF surveys in Papua New Guinea between 1980 and 2011. Results were extracted by location, time period and test used (blood slide, immunochromatographic test (ICT) or Og4C3 ELISA) and combined by district. Three criteria schemes based on the Global Programme to Eliminate Lymphatic Filariasis guidelines, with modifications, were developed to classify and prioritize districts by prevalence level. Results of repeated surveys in the same sites were used to investigate the impact of MDA on LF prevalence over the time period. \ud \ud RESULTS\ud \ud There were 312 distinct survey sites identified in 80 of the 89 districts over the 31-year period. The overall LF prevalence in the sites tested was estimated at 18.5 to 27.5% by blood slide for microfilariae (Mf), 10.1% to 12.9% by ICT and 45.4% to 48.8% by Og4C3. Biases in site selection towards areas with LF, and change in type of assay used, affected the prevalence estimates, but overall decline in prevalence over the time period was observed. Depending on the criteria used, 34 to 36 districts (population 2.7 to 2.9 million) were classed as high endemic (>=5% prevalence), 15 to 25 districts (1.7 to 1.9 million) as low endemic ( |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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