Autor: |
Chan, H.-F., Smith, L.J., Biancardi, A.M., Bray, J., Marshall, H., Hughes, P.J.C., Collier, G.J., Rao, M., Norquay, G., Swift, A.J., Hart, K., Cousins, M., Watkins, W.J., Wild, J.M., Kotecha, S. |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
ISSN: |
1073-449X |
Popis: |
Rationale: Preterm birth is associated with low lung function in childhood, but little is known about the lung microstructure in childhood. Objectives: We assessed the differential associations between the historical diagnosis of bronchopulmonary dysplasia (BPD) and current lung function phenotypes on lung ventilation and microstructure in preterm-born children using hyperpolarised 129Xe ventilation and diffusion-weighted MRI, and multiple breath washout (MBW). Methods: Data were available from 63 children (aged 9-13 years) including 44 born preterm (≤34 weeks’ gestation) and 19 term-born controls (≥37 weeks’ gestation). Preterm-born children were classified, using spirometry, into prematurity-associated obstructive lung disease (POLD, FEV1 |
Databáze: |
OpenAIRE |
Externí odkaz: |
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