Outcomes of SARS-CoV-2 infection among children and young people with pre-existing rheumatic and musculoskeletal diseases

Autor: Kearsley-Fleet, Lianne, Chang, Min-Lee, Lawson-Tovey, Saskia, Costello, Ruth, Fingerhutová, Šárka, Švestková, Natálie, Belot, Alexandre, Aeschlimann, Florence A, Melki, Isabelle, Koné-Paut, Isabelle, Eulert, Sascha, Kallinich, Tilmann, Berkun, Yackov, Uziel, Yosef, Raffeiner, Bernd, Oliveira Ramos, Filipa, Clemente, Daniel, Dackhammar, Christina, Wulffraat, Nico M, Waite, Helen, Strangfeld, Anja, Mateus, Elsa F, Machado, Pedro M, CARRA Registry Investigators, COVID-19 Global Pediatric Rheumatology Database Investigators, Natter, Marc, Hyrich, Kimme L
Jazyk: angličtina
Rok vydání: 2022
ISSN: 0003-4967
Popis: OBJECTIVES: Some adults with rheumatic and musculoskeletal diseases (RMDs) are at increased risk of COVID-19-related death. Excluding post-COVID-19 multisystem inflammatory syndrome of children, children and young people (CYP) are overall less prone to severe COVID-19 and most experience a mild or asymptomatic course. However, it is unknown if CYP with RMDs are more likely to have more severe COVID-19. This analysis aims to describe outcomes among CYP with underlying RMDs with COVID-19. METHODS: Using the European Alliance of Associations for Rheumatology COVID-19 Registry, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry, and the CARRA-sponsored COVID-19 Global Paediatric Rheumatology Database, we obtained data on CYP with RMDs who reported SARS-CoV-2 infection (presumptive or confirmed). Patient characteristics and illness severity were described, and factors associated with COVID-19 hospitalisation were investigated. RESULTS: 607 CYP with RMDs
Databáze: OpenAIRE