| Autor: |
Caplen, G., Baker, L., Hothersall, B., McKeegan, D.E.F., Sandilands, V., Sparks, N.H.C., Waterman-Pearson, A.E., Murrell, J.C. |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| ISSN: |
1090-0233 |
| Popis: |
Pain associated with poultry lameness is poorly understood. The anti-nociceptive properties of two non-steroidal anti-inflammatory drugs (NSAIDs) were evaluated using threshold testing in combination with an acute inflammatory arthropathy model. Broilers were tested in six groups (n = 8 per group). Each group underwent a treatment (saline, meloxicam (3 or 5 mg/kg) or carprofen (15 or 25 mg/kg)) and a procedure (Induced (arthropathy-induction) or sham (sham-handling)) prior to testing. Induced groups had Freund’s complete adjuvant injected intra-articularly into the left intertarsal joint (hock). A ramped thermal stimulus (1 °C/s) was applied to the skin of the left metatarsal. Data were analysed using random-intercept multi-level models.\ud \ud Saline-induced birds had a significantly higher skin temperature (± SD) than saline-sham birds (37.6 ± 0.8 °C vs. 36.5 ± 0.5 °C; Z = −3.47, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect