Impact of vitamin D on cardiac structure and function in chronic kidney disease patients with hypovitaminosis D: a randomized controlled trial and meta-analysis

Autor: Banerjee, D, Chitalia, N, Ster, IC, Appelbaum, E, Thadhani, R, Kaski, JC, Goldsmith, D
Jazyk: angličtina
Rok vydání: 2021
ISSN: 2055-6845
Popis: Aims\ud Vitamin D deficiency is associated with cardiovascular events in chronic kidney disease (CKD) yet the impact of supplementation is controversial. Previous active vitamin D supplementation studies did not show improvement in cardiac structure or function but the effect of native vitamin D supplementation in CKD patients with low vitamin D levels is unknown. We have addressed this question via both a randomized double-blind prospective study and a meta-analysis of three randomized placebo-controlled studies.\ud \ud Methods and results\ud We conducted a randomized double-blind, placebo-controlled trial of vitamin D supplementation in stable, non-diabetic, CKD three to four patients with circulating vitamin D
Databáze: OpenAIRE