| Autor: |
Tanaka, Yasuhito, Mizokami, Masashi, Orito, Etsuro, Ohba, Ken-ichi, Kato, Takanobu, Kondo, Yutaka, Mboudjeka, Innocent, Zekeng, Leopold, Kaptue, Lazare, Bikandou, Blaise, M'Pele, Pierre, Takehisa, Jun, Hayami, Masanori, Suzuki, Yoshiyuki, Gojobori, Takashi |
| Jazyk: |
angličtina |
| Předmět: |
|
| Zdroj: |
FEBS Letters. (2):143-148 |
| ISSN: |
0014-5793 |
| DOI: |
10.1016/S0014-5793(98)00083-0 |
| Popis: |
Ninety-four GB virus C/hepatitis G virus (GBV-C/HGV) RNA-positive serum samples were obtained from all over the world. We found that all 15 GBV-C/HGV isolates from the Pygmies and the Bantu in the Central African region had a 12-amino acid indel (i.e. insertion or deletion) in the non-structural protein (NS) 5A region. Phylogenetic analyses of the NS5A region, using GBV-A as an outgroup, showed that these 15 isolates had diverged from the common ancestor much earlier than the remaining isolates, indicating an African origin of GBV-C/HGV. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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