Reduced glomerular filtration rate in asymptomatic diabetic patients Predictor of increased risk for cardiac events independent of albuminuria

Autor: Knobler, Hilla, Zornitzki, Taiba, Vered, Shiraz, Oettinger, Michael, Levy, Rosa, Caspi, Abraham, Faraggi, David, Livschitz, Shay
Jazyk: angličtina
Předmět:
Zdroj: Journal of the American College of Cardiology. (11):2142-2148
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2004.09.006
Popis: ObjectivesThis study aimed to investigate the prevalence of a reduced glomerular filtration rate (GFR) with and without albuminuria and its ability to predict cardiac events in asymptomatic diabetic patients undergoing stress-rest thallium-201 myocardial perfusion single-photon emission computed tomography.BackgroundDiabetic patients have a higher prevalence of asymptomatic coronary heart disease. Therefore, identifying predictors of cardiac events in asymptomatic diabetic patients is needed.MethodsIn 269 asymptomatic patients, baseline evaluation included diabetes-related complications, including creatinine clearance (CrCl) and albuminuria. During follow-up (mean 2.3 ± 1.0 years), all cardiac events were recorded.ResultsSeventy-seven patients (29%) had a reduced GFR defined by CrCl
Databáze: OpenAIRE