Randomised controlled trial and economic evaluation of a targeted cancer awareness intervention for adults living in deprived areas of the UK

Autor: Moriarty, Y., Lau, M., Sewell, B., Trubey, R., Quinn-Scoggins, H., Owen, S., Padgett, L., Kolovou, V., Hepburn, J., Buckle, P., Playle, R., Townson, J., Robling, M., Gilbert, S., Dimitropoulou, P., Edwards, A., Mitchell, C., Matthews, M., Smits, S., Wood, F., Neal, R.D., Brain, K.
Jazyk: angličtina
Rok vydání: 2021
ISSN: 0007-0920
Popis: Background: Cancer outcomes are poor in socioeconomically deprived communities, with low symptom awareness contributing to prolonged help-seeking and advanced disease. Targeted cancer awareness interventions require evaluation.\ud \ud \ud Methods: Randomised controlled trial involving adults aged 40+ recruited in community and healthcare settings in deprived areas of South Yorkshire and South-East Wales. Intervention: personalised behavioural advice facilitated by a trained lay advisor. Control: usual care. Follow-up at 2-weeks and 6-months post-randomisation. Primary outcome: total cancer symptom recognition score 2-weeks post-randomisation. \ud \ud \ud Results: 234 participants were randomised. The difference in total symptom recognition at 2-weeks [adjusted mean difference (AMD) 0.6, 95% CI:-0.03, 1.17, p=0.06] was not statistically significant. Intervention participants reported increased symptom recognition (AMD 0.8, 95% CI:0.18, 1.37, p=0.01) and earlier intended presentation (AMD -2.0, 95% CI:-3.02, -0.91, p
Databáze: OpenAIRE