Risk factors associated with short‐term mortality and recurrence of status epilepticus in dogs

Autor: Fentem, Rory, de Stefani, Alberta, Gutierrez Quintana, Rodrigo, Alcoverro, Emili, Jones, Gareth Michael Couper, Amengual-Batle, Pablo, Gonçalves, Rita
Jazyk: angličtina
Rok vydání: 2022
ISSN: 0891-6640
Popis: Background:\ud Status epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited.\ud \ud Objective:\ud Identify risk factors associated with short-term mortality (euthanasia or spontaneous death) and recurrence of SE in dogs.\ud \ud Animals:\ud One hundred twenty-four client-owned dogs that sustained an episode of SE.\ud \ud Methods:\ud Retrospective multicenter study using data collected from medical records of dogs presented in SE to the contributing institutions. Multivariable logistic regression analysis was performed using a manual backwards stepwise approach to identify risk factors associated with short-term mortality and recurrence of SE after discharge.\ud \ud Results:\ud Short-term mortality for affected dogs was 29.8%. Factors significantly associated with short-term mortality included increased patient age, shorter duration of hospitalization, development of SE before arrival, and SE caused by a potentially fatal etiology. Status epilepticus recurred in 27% of dogs that survived to discharge. Factors significantly associated with recurrence of SE included prior history of pharmacoresistant epilepsy and predominance of a focal seizure phenotype.\ud \ud Conclusions and Clinical Importance:\ud Our results may be used to inform clinicians and dog owners regarding risk factors for both short-term mortality and recurrence in dogs with SE.
Databáze: OpenAIRE