An advanced sheep (Ovis aries, 2n=54) cytogenetic map and assignment of 88 new loci by fluorescent in situ hybridization and R-banding

Autor: Di Meo GP, Perucatti A, Floriot S, Hayes H, Schibler L, Rullo R, Incarnato D, Ferretti L, Cockett N, Cribu E, Williams JL, Eggen A, Iannuzzi L.
Jazyk: angličtina
Rok vydání: 2007
Zdroj: Animal genetics
38 (2007): 233–240. doi:10.1111/j.1365-2052.2007.01598.x
info:cnr-pdr/source/autori:Di Meo GP, Perucatti A, Floriot S, Hayes H, Schibler L, Rullo R, Incarnato D, Ferretti L, Cockett N, Cribu E, Williams JL, Eggen A, Iannuzzi L./titolo:An advanced sheep (Ovis aries, 2n=54) cytogenetic map and assignment of 88 new loci by fluorescent in situ hybridization and R-banding./doi:10.1111%2Fj.1365-2052.2007.01598.x/rivista:Animal genetics (Print)/anno:2007/pagina_da:233/pagina_a:240/intervallo_pagine:233–240/volume:38
DOI: 10.1111/j.1365-2052.2007.01598.x
Popis: Presented herein is an updated sheep cytogenetic map that contains 452 loci (291 type I and 161 type II) assigned to specific chromosome bands or regions on standard R-banded ideograms. This map, which significantly extends our knowledge of the physical organization of the ovine genome, includes new assignments for 88 autosomal loci, including 74 type I loci (known genes) and 14 type II loci (SSRs/microsatellite marker/STSs), by FISH-mapping and R-banding. Comparison of the ovine map to the cattle and goat cytogenetic maps showed that common loci were located within homologous chromosomes and chromosome bands, confirming the high level of conservation of autosomes among ruminant species. Eleven loci that were FISH-mapped in sheep (B3GAT2, ASCC3, RARSL, BRD2, POLR1C, PPP2R5D, TNRC5, BAT2, BAT4, CDC5L and OLA-DRA) are unassigned in cattle and goat. Eleven other loci (D3S32, D1S86, BMS2621, SFXN5, D5S3, D5S68, CSKB1, D7S49, D9S15, D9S55 and D29S35) were assigned to specific ovine chromosome (OAR) bands but have only been assigned to chromosomes in cattle and goat.
Databáze: OpenAIRE
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