Structure and dynamics of materials by NMR spectroscopy and relaxometry: research activities at the Pisa Solid State NMR joint laboratory
| Autor: | Silvia Borsacchi, Lucia Calucci, Elisa Carignani, Claudia Forte, Marco Geppi, Francesca Martini, Silvia Pizzanelli |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | 1st Workshop on Nuclear Magnetic Resonance Relaxometry (COST action CA15209), Olsztyn (Poland), 13-15/02/2017 info:cnr-pdr/source/autori:Silvia Borsacchi, Lucia Calucci, Elisa Carignani, Claudia Forte, Marco Geppi, Francesca Martini, Silvia Pizzanelli/congresso_nome:1st Workshop on Nuclear Magnetic Resonance Relaxometry (COST action CA15209)/congresso_luogo:Olsztyn (Poland)/congresso_data:13-15%2F02%2F2017/anno:2017/pagina_da:/pagina_a:/intervallo_pagine |
| Popis: | The Pisa Solid State NMR joint laboratory groups researchers from two institutions, the ICCOM-CNR institute and the Department of Chemistry of the University of Pisa. Its research activities encompass NMR spectroscopy and relaxometry applied to the investigation of organic, inorganic, and hybrid materials of interest for technological or biomedical applications or in relation to environmental issues. Activities relevant to the Eurelax COST Action will be presented through representative examples. Researchers with over twenty years' experience in the application of high and low resolution multi-nuclear solid state NMR techniques to structural studies of materials, as well as in the investigation of dynamic properties by measurement and analysis of longitudinal and transverse nuclear relaxation times with conventional spectrometers work in the lab. The recent acquisition of a Fast Field-Cycling relaxometer has given access to complementary information on molecular dynamics and has opened new perspectives for the laboratory research activities. In particular, investigations of structural and dynamic properties of soft (i.e. thermotropic and lyotropic liquid crystals, plastic crystals, polymers, hydrogels) and hard (i.e. polymers and composites, drugs, biochar, cements) materials are performed by multi-Nuclear MR spectroscopy and/or 1H (and 2H) relaxometry techniques. These activities are mainly of interest for WG1, but have also strong connections with WG2, WG3, and WG4. Applications of 1H NMR relaxometry experiments (i.e. T2 and T1 measurements with conventional spectrometers and T1 measurements with the FFC relaxometer) to the investigation of water dynamics and water-surface interactions in porous systems, such as biochar and cements, are also carried out, these activities being mostly pertinent to WG3. Moreover, some researchers of the laboratory are working on systems of biomedical interest of relevance to WG2, such as model membranes, nanostructured contrast agents, hydrogels for drug release and tissue engineering, and polypeptides. In particular, 1H water proton relaxation properties are investigated in relation to the interactions of water molecules with polymer chains or phospholipid molecules and cross-relaxation in diamagnetic systems (hydrogels, peptides, membranes), whereas relaxation enhancement mechanisms based on the interactions of water protons with unpaired electron spins are considered in paramagnetic ones (contrast agents, metal ions complexed to peptides). Suitable instrumentation and theoretical tools are always necessary to acquire and interpret NMR data useful to solve problems in materials science, environmental science, and biomedicine; in this respect, collaborations with members of WG4 and WG5 are envisaged. |
| Databáze: | OpenAIRE |
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