Subcellular distribution of alpha1 and beta2/3 GABAA receptor subunits in sensory neurons of the bovine trigeminal mesencephalic nucleus: evidence suggesting their axoplasmic transport

Autor:	Cupello A 1, Luccardini C. 1, Rapallino M.V. 1, Robello M. 2, Seitun A 3.
Rok vydání:	2004
Předmět:	Recettori GABA(A) nervous system subunità immunocitochimica neuroni di Deiters
Zdroj:	Neurochemical research 29 (2004): 1387–1389. info:cnr-pdr/source/autori:Cupello A 1, Luccardini C. 1, Rapallino M.V. 1, Robello M. 2, Seitun A 3./titolo:Subcellular distribution of alpha1 and beta2%2F3 GABAA receptor subunits in sensory neurons of the bovine trigeminal mesencephalic nucleus: evidence suggesting their axoplasmic transport/doi:/rivista:Neurochemical research/anno:2004/pagina_da:1387/pagina_a:1389/intervallo_pagine:1387–1389/volume:29
Popis:	Neurons were free-hand isolated under the stereomicroscope from the bovine trigeminal mesencephalic nucleus. These neurons were challenged with monoclonal antibodies against the alpha1 and the beta2/3 subunits of the GABA(A) receptor. The neurons showed a strong reaction to both antibodies. The reaction was mainly intracellular in the round cell bodies and in the axoplasm of the axon emerging from these pseudounipolar cells. This suggests the synthesis of these subunits in the cell body and their transport along the axon.
Databáze:	OpenAIRE
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