Department of Surgery, Autonomous University of Barcelona, Barcelona, Spain br

Autor: Gallioli, A, Diana, P, Fontana, M, Territo, A, Rodriguez-Faba, O, Gaya, JM, Sanguedolce, F, Huguet, J, Mercade, A, Piana, A, Aumatell, J, Bravo-Balado, A, Algaba, F, Palou, J, Breda, A
Rok vydání: 2022
Předmět:
Zdroj: European Urology Oncology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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ISSN: 2588-9311
Popis: Background: It has been proposed that en bloc resection of bladder tumor (ERBT) improves the quality of tumor resection. A recent international collaborative consensus statement on ERBT underlined the lack of high-quality prospective studies precluding the achievement of solid conclusion on ERBT.Objective: To compare conventional transurethral resection of bladder tumor (cTURBT) and ERBT.Design, setting, and participants: This study (NCT04712201) was a prospective, randomized, noninferiority trial enrolling patients diagnosed with bladder cancer (BC) undergoing endoscopic intervention. Inclusion criteria were: tumor size 0.05). The recurrence rate at median follow-up of 15 mo (interquartile range 7-28) was 18% for cTURBT versus 13% for ERBT (p = 0.16). Limitations include the single high-volume institution and the short-term follow-up. Conclusions: Our study has the highest level of evidence for comparison of ERBT versus TURBT. ERBT was noninferior to TURBT for BC staging. The rate of T1 substaging feasibilityPatient summary: We compared two techniques for removing tumors from the bladder. The en bloc technique removes the tumor in one piece and is not inferior to the conventional method in terms of the quality of the surgical resection and cancer staging assessment. (c) 2022 European Association of Urology. Published by Elsevier B.V. All rights reserved.
Databáze: OpenAIRE
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