Efectividad de la vacuna BNT162b2 para prevenir la COVID-19 en personal sanitario
| Autor: | Chico-Sánchez P, Gras-Valentí P, Algado-Sellés N, Merino-Lucas E, Rodríguez-Díaz JC, Ronda-Pérez E, Sánchez-Payá J, Grupo COVID-19 de Medicina Preventiva |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | GACETA SANITARIA r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante instname |
| ISSN: | 0213-9111 |
| Popis: | OBJECTIVE: To assess the effectiveness of the vaccine against SARS-CoV-2 (BNT162b2) in healthcare personnel of a health department. METHOD: Test-negative case?control study. Healthcare personnel with suspected COVID-19 and healthcare personnel close contacts of COVID-19 cases were included between January 27th and June 6th, 2021. They were PCR tested for SARS-CoV-2; those with positive PCR were considered cases and those with negative PCR were considered controls. The adjusted vaccine effectiveness (aVE) to prevent COVID-19 cases and their 95% confidence interval (95%CI) were calculated using the formula VE=(1-odds ratio)×100. RESULTS: 624 healthcare personnel were included, of which 43 (6.9%) were considered cases and 581 (93.8%) controls. The aVE of the complete regimen was 96.3% (95%CI: 82.5?99.2). The aVE of the incomplete pattern was 68.0% (95%CI: 30.0?85.4). CONCLUSIONS: The administration of the complete pattern of BNT162b2 vaccine against SARS-CoV-2 is effective for the prevention of cases of COVID-19 in healthcare personnel. |
| Databáze: | OpenAIRE |
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