Rationale and design of the optical coherence tomography observation of pulmonary ultra-structural changes in heart failure (OCTOPUS-CHF) study

Autor: Ortiz-Bautista, C, Gutierrez-Ibanes, E, Garcia-Cosio, MD, Calvino-Santos, R, Gomez-Bueno, M, Mirabet-Perez, S, Gomez-Hospital, JA, Lambert-Rodriguez, JL, Garrido-Bravo, IP, Galan, LD, Mombiela, T, Martinez-Solano, J, Martinez-Selles, M
Rok vydání: 2020
Předmět:
Zdroj: INTERNATIONAL JOURNAL OF CARDIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ISSN: 0167-5273
Popis: Background: The assessment of vascular remodeling using optical coherence tomography (OCT) has been previously described in some types of pulmonary hypertension. However, evidence about its feasibility and clinical utility for evaluation of pulmonary arterial vasculopathy in advanced heart failure (HF) is scarce. Optical Coherence Tomography Observation of Pulmonary Ultra-Structural Changes in Heart Failure (OCTOPUS-CHF) study is designed to study the correlation between OCT-morphometric parameters and hemodynamic data measured or derived from right heart catheterization (RHC). Methods: OCTOPUS-CHF is an observational, prospective, multicentre study aiming to recruit 100 patients with advanced HF referred for heart transplantation (HTx) evaluation. As part of such evaluation, all patients will undergo RHC in order to rule out severe pulmonary hypertension. After RHC, a Dragonfly (TM) OPTIS (TM) imaging catheter will be used to perform OCT evaluation of a right-lower-lobe pulmonary artery with a luminal diameter
Databáze: OpenAIRE
Externí odkaz: