Soluble TNF receptors predict acute kidney injury and mortality in critically ill COVID-19 patients: A prospective observational study

Autor: Sancho Ferrando, Elena, Hanslin, Katja, Hultström M, Larsson, Anders, Frithiof, Robert, Lipcsey, Miklos, Uppsala Intensive Care COVID-19 Research Group
Rok vydání: 2022
Předmět:
Zdroj: Cytokine
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
ISSN: 1043-4666
Popis: Although pneumonia is the hallmark of coronavirus disease 2019 (COVID-19), multiple organ failure may develop in severe disease. TNFa receptors in their soluble form (sTNFR) are involved in the immune cascade in other systemic inflammatory processes such as septic shock, and could mediate the inflammatory activation of distant organs. The aim of this study is to analyse plasma levels of sTNFR 1 and 2 in association with organ failure and outcome in critically ill patients with COVID-19.
Databáze: OpenAIRE
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