Biomarkers of the prothrombotic state in abdominal obesity
| Autor: | Montilla,Marcela, Santi,María José, Carrozas,María A., Ruiz,Félix A. |
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| Rok vydání: | 2015 |
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| Zdroj: | Nutrición Hospitalaria v.31 n.3 2015 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| Popis: | Introduction: Central obesity is specifically associated with cardiovascular disease. Nevertheless, the molecular events that promote these conditions remain incompletely defined and risk stratifying patients for cardiovascular disease continues a challenge. Objective: The aim of this study was to assess some cost-efficient haemostatic markers, and its association with central obesity and traditional cardiovascular risk factors, in a cohort of middle aged subjects, without clinical cardiovascular disease, as basis for an improved prevention and intervention. Methods: We studied 307 men, aged 45±7 years, which underwent medical history, physical examination, anthropometric measurements, plasmatic biochemical parameters, plasma concentrations of fibrinogen, prothrombin activity, activated partial thromboplastin time, platelet count and mean platelet volume. Results: Prothrombin activity values were significantly higher in patients with central obesity (103 ± 16 % vs 111 ± 17 %, p |
| Databáze: | OpenAIRE |
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