Determination of Anti-Anisakis Simplex Antibodies and Relationship with aß and ?d Lymphocyte Subpopulations in Patients with Crohn's Disease

Autor: Benet-Campos C, Cuéllar C, García-Ballesteros C, Zamora V, Gil-Borrás R, Catalán-Serra I, López-Chuliá F, Andreu-Ballester JC
Rok vydání: 2017
Předmět:
Zdroj: DIGESTIVE DISEASES AND SCIENCES
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
ISSN: 0163-2116
Popis: The etiology of Crohn's disease (CD) is still unknown although new theories are based on defects in innate immunity. We have previously shown a decrease in ?d T cells in CD patients. Previous studies have shown a high prevalence of anti-A. simplex immunoglobulins in CD patients. The diminution of ?d T cells in the peripheral blood and intestinal mucosa of CD patients may create a state of immunosuppression that would facilitate A. simplex infection.
Databáze: OpenAIRE
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