Enzymatic Synthesis of Polyesters and Their Bioapplications: Recent Advances and Perspectives

Autor: Hevilla, V., Sonseca, Águeda, Echeverría, Coro
Přispěvatelé: Ministerio de Ciencia, Innovación y Universidades (España), European Commission
Rok vydání: 2021
Předmět:
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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Popis: This article reviews the most important advances in the enzymatic synthesis of polyesters. In first place, the different processes of polyester enzymatic synthesis, i.e., polycondensation, ring opening, and chemoenzymatic polymerizations, and the key parameters affecting these reactions, such as enzyme, concentration, solvent, or temperature, are analyzed. Then, the latest articles on the preparation of polyesters either by direct synthesis or via modification are commented. Finally, the main bioapplications of enzymatically obtained polyesters, i.e., antimicrobial, drug delivery, or tissue engineering, are described. It is intended to point out the great advantages that enzymatic polymerization present to obtain polymers and the disadvantages found to develop applied materials. This work was funded by the MICINN (PID2019-104600RB-I00), the Agen- cia Estatal de Investigación (AEI, Spain), and Fondo Europeo de Desarrollo Regional (FEDER, EU). A.S. acknowledges her “PAID-10-19” postdoctoral contract from the Polytechnic University of Valencia.
Databáze: OpenAIRE