Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease

Autor:	López, Alicia, Aparicio, Noelia, Pazos, M Ruth, Grande, M Teresa, Barreda-Manso, M Asunción, Benito-Cuesta, Irene, Vázquez, Carmen, Amores, Mario, Ruiz-Pérez, Gonzalo, García-García, Elena, Beatka, Margaret, Tolón, Rosa M, Dittel, Bonnie N, Hillard, Cecilia J, Romero, Julián
Rok vydání:	2018
Předmět:	Amyloid Green Fluorescent Proteins Mice Transgenic Plaque Amyloid Receptor Cannabinoid CB2 Mice Neuroinflammation Alzheimer Disease Transgenic mice Animals Cannabinoid CB2 receptor Enhanced green fluorescent protein Analysis of Variance Amyloid beta-Peptides CD11b Antigen Calcium-Binding Proteins Microfilament Proteins Brain Flow Cytometry Peptide Fragments Mice Inbred C57BL Disease Models Animal Gene Expression Regulation Phosphopyruvate Hydratase lipids (amino acids peptides and proteins) Microglia
Zdroj:	Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid Consejería de Sanidad de la Comunidad de Madrid
Popis:	Because of their low levels of expression and the inadequacy of current research tools, CB2 cannabinoid receptors (CB2R) have been difficult to study, particularly in the brain. This receptor is especially relevant in the context of neuroinflammation, so novel tools are needed to unveil its pathophysiological role(s).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::6106183f1567f20fd9c2de4df6a12c30 https://hdl.handle.net/20.500.12530/43374 Zobrazit plný text záznamu