PHYSICAL FRAILTY IN LIVER TRANSPLANTATION
| Autor: | Puchades Renau L, Herreras López J, Cebrià I Iranzo MÀ, Cezón Serrano N, Berenguer Haym M |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe instname |
| ISSN: | 1130-0108 |
| Popis: | In patients with cirrhosis, frailty represents a status of global physical dysfunction caused by undernutrition, muscle wasting and functional impairment. It is a prevalent condition in liver transplant (LT) candidates and has shown to be an independent predictor of adverse outcome. Evidence supports its incorporation into clinical practice both as a prognostic factor guiding clinical decision-making, and as a tool to identify candidates for physical and nutritional interventions. The wide heterogeneity of instruments used for frailty measurement, the absence of a single suitable instrument for frailty assessment in all LT clinical scenarios (inpatient vs outpatient; pre-transplant vs post-transplant), and the lack of strong evidence showing a beneficial effect of frailty improvement on outcomes before and after transplantation are some of the questions that remain unanswered. |
| Databáze: | OpenAIRE |
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