Unambiguous Intracellular Localization and Quantification of a Potent Iridium Anticancer Compound by Correlative 3D Cryo X-Ray Imaging
| Autor: | Conesa J.J., Carrasco A.C., Rodríguez-Fanjul V., Yang Y., Carrascosa J.L., Cloetens P., Pereiro E., Pizarro A.M. |
|---|---|
| Přispěvatelé: | We thank C. Pati?o and B. Mart?n from Electron Microscopy Unit (CNB-CSIC) for preparing the ultrathin sections and for accommodating the TEM work. Dr. A. Arn?iz (IMDEA Nanociencia) is gratefully acknowledged for assistance with cell culture techniques. We acknowledge funding from the EC (FP7-PEOPLE-2013-CIG, No. 631396), from the MINECO of Spain (RYC-2012?11231, CTQ2014-60100-R, SEV-2016-0686, BFU 2014?54181-P, and CTQ2017-84932-P), and from the Comunidad Aut?noma de Madrid (S2013/MIT- 2850). Cryo-SXT experiments were performed at MISTRAL beamline at ALBA Synchrotron with the collaboration of ALBA staff (2017022061). Cryo-XRF experiments were performed at ID16A beamline at ESRF Synchrotron with the collaboration of ESRF staff, in the frame of proposals LS2767 (doi:10.15151/ESRF-ES-112668425) and IHLS3102 (doi:10.15151/ESRF-ES-103850884). |
| Rok vydání: | 2020 |
| Zdroj: | Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA Nanociencia) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|