Seroprevalence of anti-SARS-CoV-2 IgG antibodies: relationship with COVID-19 diagnosis, symptoms, smoking, and method of transmission [Recurso electrónico]
| Autor: | Bühler, Kora Mareen., Echeverry-Alzate, Víctor., Calleja Conde, Javier., Durán González, Pedro., Segovia Rodríguez, Lucía., Morales García, José A., Pérez Wiesner, Mateo., Cables Chozas, David., Rodríguez de Fonseca, Fernando., Delgado-Iribarren, Alberto., Merino Amador, Paloma., González Romo, Fernando., Giné Domínguez, Elena., López Moreno, José Antonio., Universidad Antonio de Nebrija. Grupo Nebrija de Investigación Brain and Behaviour (Cerebro y Comportamiento) (BRABE) |
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| Rok vydání: | 2022 |
| Zdroj: | Repositorio Nebrija Universidad de Nebrija |
| Popis: | Aims: The study of SARS-CoV-2 antibodies in the population is a crucial step towards overcoming the COVID-19 pandemic. Seroepidemiological studies allow an estimation of the number of people who have been exposed to the virus, as well as the number of people who are still susceptible to infection. Methods: In total, 13 560 people from Arganda del Rey, Madrid (Spain) were assessed between January and March 2021 for the presence of IgG antibodies, using rapid tests and histories of symptoms compatible with COVID-19. Results: 24.2% of the participants had IgG antibodies and 9% had a positive COVID-19 diagnosis. Loss of smell/taste was the most discriminating symptom of the disease. The main transmitters of infection were found to be household members. Unexpectedly, in smokers, the incidence of positive COVID-19 diagnoses was significantly lower. Additionally, it was found that there was a discrepancy between COVID-19 diagnosis and the presence of IgG antibodies. Conclusions: Rapid anti-IgG tests are less reliable in detecting SARS-CoV-2 infection at an individual level, but are functional in estimating SARS-CoV-2 infection rates at an epidemiological level. The loss of smell/taste is a potential indicator for establishing COVID-19 infection. Sitio web de la revista (Consulta: 07-10-2022) |
| Databáze: | OpenAIRE |
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