The hypoglycemic effect of aqueous leaf extract of aloes in alloxan-induced diabetic albino rats

Autor: Olorunfemi, OJ, Nworah, DC, Joffa, PPK, Chinko, BC
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: International Journal of Natural and Applied Sciences; Vol 7, No 4 (2011); 381 – 385
ISSN: 0794-4713
Popis: The hypoglycemic effect of aqueous leaf extract of aloes was studied in alloxan-induced diabetic albino winster rats. Twenty five mature rats used in the study were randomly divided into five groups with five rats in each group. Group C served as the control and received no drug. Group 1was treated with water; group 2 was treated with the plant extract at 1000 mg/kg; group 3 was treated with the drug glibenclamide (10 mg/kg) and group 4 with a combination therapy (500 mg/kg aloes extract and 5 mg/kg Glibenclamide). The rats were fed ad libitum in 14 day experiment. At 3 days intervals, the blood sample was collected to determine the glucose level in all the different groups. When compared with the standard drug gluburide, the glucose lowering effect of aqueous extract of aloes was significantly at p
Databáze: OpenAIRE