Genes Underlying Positive Influence Of Prenatal Environmental Enrichment And Negative Influence Of Prenatal Earthquake Simulation And Corrective Influence Of Chinese Herbalmedicine On Rat Offspring: Irf7 And Ninj2

Autor: Zhang, XG, Zhang, H, Lin, L, Yang, YQ, Deng, TT, Liu, Q, Liang, XL, Wang, MQ, Peng, DZ
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: African Journal of Traditional, Complementary and Alternative Medicines; Vol 11, No 2 (2014); 367-376
ISSN: 0189-6016
Popis: Background: Prenatal environmental enrichment (EE) has been proven to positively affect but prenatal stress negatively influence the physiological and psychological processes in animals, whose trans-generational genetic mechanism remains unclearly defined. We aimed to investigate and find out key genes underlying the positive-negative effects derived from prenatal interventions.Materials and Methods: Pregnant rats were randomized into EE group (EEG), earthquake simulation group (ESG), herbal group (HG) received herbal supplements in feed after earthquake simulation, and control group (CG).Results: Light Box Defecation Test (LBDT) showed EEG offspring presented less fecal pellets than CG offspring, ESG’s more than CG’s, and HG’s less than ESG (p’s
Databáze: OpenAIRE