Prevalence of selective IgA deficiency in a sample of Egyptian patients with type 1 diabetes mellitus
| Autor: | Elsayed, Hoda Mohamed, Ali, Fawzia Hassan Abou, Sheha, Dina Sayed, Ibrahim, Nesma Ali, Sharawy, Yasmin Sayed, Kamal, Sylvia Talaat |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Egyptian Journal of Hospital Medicine; Vol. 86 No. 1 (2022); 17-21 |
| ISSN: | 1687-2002 2090-7125 |
| Popis: | Background: Selective Immunoglobulin A deficiency (SIgAD) is known to be one of the most frequent primary immunodeficiency diseases. Several studies worldwide confirm the increased frequency of this disease among type 1 diabetes mellitus (T1DM), yet this has not been studied in Egypt.Objective: This work aimed to define the prevalence of SIgAD among Egyptian patients with T1DM.Patients and Methods: Fifty patients with T1DM were compared to fifty apparently healthy individuals. Serum levels of IgA, IgG, and Immunoglobulin M (IgM) levels were measured by Nephelometry to all participants.Results: The mean age of the diabetic group was 24.5 ± 5.3 years. Thirty out of fifty patients with T1DM (60%) were diagnosed as SIgAD with, female predominance (66.7% of SIgAD). We also found a significant relationship between SIgAD and diabetic ketoacidosis (P-value |
| Databáze: | OpenAIRE |
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