Hypoglycemic and hypolipidemic activity of methanolic leaf extract of Morinda lucida on alloxan induced diabetic rats

Autor: Haruna, Hauwa M.S., Gabi, Baba, Jere, Saudatu Ahmad
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Bayero Journal of Pure and Applied Sciences; Vol 10, No 2 (2017); 48-51
ISSN: 2006-6996
Popis: Healthy male wistar rats(30) of average weight of 150 – 190gm were randomly distributed into 5 gr. oups of six each. Group 1, normal control; each given only 0.2ml distilled water throughout the period of study; group 2 diabetic control, induced 150mg/kg b.w., i.p., administration of alloxan monohydrate and thereafter given 0.2ml distilled water throughout the period of study; group 3 and 4 diabetic (i.p., 150mg/kg b.w. alloxan), rats were orally administered methanolic leaf extract of Morinda lucida at 100mg/kg and 200mg/kg respectively for 15 days. Group 5 diabetic rat (i.p., 150mg/kg b.w. alloxan) were treated with 84mg/kg /b.w. of chlorpropamide once daily for 15 days. Serum glucose levels were found to decrease significantly (p
Databáze: OpenAIRE