case Report: A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab

Autor: Kirui, N, Sokwala, A
Jazyk: angličtina
Rok vydání: 2016
Zdroj: South African Medical Journal; Vol 106, No 7 (2016); 689-691
ISSN: 2078-5135
0256-9574
Popis: Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving protease (ADAMTS13) due to autoantibodies that are directed towards ADAMTS13. We report a case of a 46-year-old man who presented with most of the classic clinical manifestations of TTP.
Databáze: OpenAIRE