Xylocaine® 10% Pump Spray as topical anaesthetic for venepuncture pain
| Autor: | van Straten, A, Murray, A.A., Levin, A.I. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Southern African Journal of Anaesthesia and Analgesia; Vol 24, No 3 (2018); 75-78 |
| ISSN: | 2220-1181 2220-1173 |
| Popis: | Background: Cutaneous analgesia for venepuncture pain can be achieved using various topically applied local anaesthetic formulations. Xylocaine®10% Pump Spray containing lignocaine hydrochloride and 95% ethanol is exclusively recommended for mucosal anaesthesia. However, this formulation is readily able to penetrate skin. This study investigated whether topical pretreatment with Xylocaine® 10% Pump Spray could facilitate analgesia for venepuncture.Methods: A single-centre, prospective, randomised, double-blind placebo-controlled trial was conducted. One hundred patients were enrolled. The control and intervention groups had 0.5 ml saline and 0.5 ml Xylocaine®applied for 20 min to preselected venepuncture sites. Pain associated with an 18-gauge cannula venepuncture was rated on an 11-point Numerical Rating Scale. A two-point or 30% reduction in pain would be deemed clinically significant.Results: Pain scores were lower (p= 0.001) in the Xylocaine® (median 2; 95% CI 2–3) than the saline (median 4; 95% CI 3–5) group. Moderate-to-severe pain occurred in fewer Xylocaine® (18%) than saline (42%) treated patients (relative risk 0.43, CI 0.22 to 0.48; NNT = 5).Conclusion:Topical Xylocaine®10% Pump Spray pre-treatment provided a time-effective method of reducing venepuncture associated pain.Keywords:local anaesthesia, venepuncture pain, Xylocaine® 10% Pump Spray |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|