| Autor: |
Ijioma, Solomon, Osim, Eme, Nwankwo, Azubike, Kanu, Kingsley, Orieke, Daniel, Ezike, Johnson |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Animal Research International; Vol 16, No 3 (2019); 3494 – 3502 |
| ISSN: |
1597-3115 |
| Popis: |
The antimotility effect of Ajumbise polyherbal extract (APE) and its composite plants were evaluated in-vitro and in-vivo. In the in-vitro study, about 2 – 3 cm of a rabbit jejunum mounted in a 30 ml organ bath containing tyrode solution and bubbled with air was set up before the applications of graded doses of acetylcholine and extracts. In the in-vivo study, 16 groups of 5 rats each were pretreated with the extracts and atropine followed by charcoal meal after 30 minutes before being sacrificed 30 minutes later and opened up to assess gastrointestinal transit of the administered charcoal meal. Application of acetylcholine caused a dose dependent increase in the amplitude of contraction when compared with basal value (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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