Lipid-Lowering Activity of the Leaf Extracts of Vitex doniana in Cholesterol-Fed Guinea Pigs

Autor: Okwuosa, CN, Achukwu, PU, Udeani, TK, Azubuike, NC, Uguru, DI
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: West African Journal of Pharmacology and Drug Research; Vol 26 (2010); 36-42
ISSN: 0303-691X
Popis: The effect of the aqueous and methanol extracts of Vitex doniana on serum lipid profile of cholesterol fed guinea–pigs was investigated. Intraperitoneal graded doses (50 and 100mg/kg) of the aqueous and methanol extracts of Vitex doniana (AEVD and MEVD) were administered to guinea-pigs in respective groups prior to cholesterol gavage (1000mg/kg). Two other groups served as the positive control and the baseline control respectively. Results showed significant increase in mean total cholesterol levels of treated groups when compared with baseline value (p
Databáze: OpenAIRE